Development and Validation of Granulometric Analytical Methods The development and validation of granulometric analytical methods are essential processes in the analysis of solid particles present in samples of various kinds. These methods are used in sectors such as the pharmaceutical, food, environmental, and mining industries to determine the particle size distribution. In this context, the company IMS Srl, located at Via Venezia Giulia 23 in Milan, stands out as a point of reference thanks to its experience and expertise in micronization and granulometric analysis.
Analytical Method Development
The first step in the development of a granulometric analytical method is the identification of the most suitable analytical method for the characteristics of the sample under examination. Common techniques include sedimentation, optical microscopy, laser diffraction, and light diffraction laser spectroscopy. Thanks to its technologies and highly qualified staff, IMS Srl is able to identify the most appropriate method and instrument for each specific material, ensuring the accuracy and precision of the results.
Optimization of Parameters
During method development, it is essential to optimize experimental parameters to ensure accurate and reproducible results. This phase involves evaluating critical parameters such as the choice of dispersion method, solvent, most suitable adjuvants, and the most effective instrumental parameters. Thanks to its accumulated experience, IMS Srl is able to maximize the sensitivity of the method and minimize experimental errors, offering tailor-made solutions for every need.
Analytical Method Validation
The validation of a granulometric analytical method is a complex process aimed at ensuring that the method is suitable for its intended use and provides accurate and precise results. IMS Srl conducts validation in accordance with international guidelines, such as those described in the most widespread pharmacopoeias and ISOs, ensuring that the developed methods are reliable and comply with global standards.
Quality Control
Once the validation is completed, the analytical method can be used for routine quality control analyses of products that have entered the production process. IMS Srl also adopts regular monitoring of instrumental performance and continuous updating of laboratory personnel. This approach ensures the reliability and repeatability of the results obtained.
The development and validation of granulometric analytical methods require careful planning, accurate optimization of experimental parameters, and strict compliance with regulatory requirements. IMS Srl of Milan, with its experience and expertise in the field, represents the ideal partner to face these challenges, offering customized solutions that support critical decisions in various application sectors.
Are you interested in improving the accuracy and reliability of your granulometric analyses? Contact IMS Srl to find out how the company can support you in achieving your analytical goals.
