WHAT IS MICRONIZATION?
What is micronization?
Pharma Micronization is an advanced technique that allows to reduce the dimensions of particles of an active pharmaceutical ingredient or an eccipient.
How is micronization carried out?
The material is injected under high pressure in a griding chamber using gas flow ( compressed air or nitrogen). The particles of the material dragged by the flow at very high speed, due to the geometry of the chamber, are subjected to speed and direction variations with auto collision and consequent dimension reduction to values settled by the operative condition of the process.
Why micronization is used?
Micronization is used to follow the particle size requirements for the active ingredient and /or excipients, necessary to fit the formulation parameters on the final dosage form.
When is it necessary to resort to micronization?
Micronization is used to meet the particle size requirements of the active ingredients and excipients, steroids micronization, hormones micronization, particle size reduction, parameters that are very often fundamental for the formulation of the finished product and necessary for obtaining the desired bioavailability of the same.